Endocrine Abstracts

Type 1 diabetes mellitus (T1DM) and preeclampsia (PE) in pregnant women share common pathophysiological pattern (hypovolemia, increased vascular resistance, and kidney damage) and both are genetically determined. Genetic impact on PE development and aggravation of insulin resistance in T1DM pregnant women has been underinvestigated. Thus, the aim of this case-control study was to evaluate the influence of ACE gene I/D polymorphism on risk of PE and insulin re...